Benefit/risk assessment in clinical research
نویسندگان
چکیده
منابع مشابه
Lessons From Memory Assessment in Research and Clinical Practice
An examination of test manuals and published research indicates that widely used memory tests (e.g., Verbal Paired Associates and Word List tests of the Wechsler Memory Scale, Rey Auditory Verbal Learning Test, and California Verbal Learning Test) are afflicted by severe ceiling effects. In the present study, the true extent of memory ability in healthy young adults was tested by giving 208 col...
متن کاملAssessment of regional analgesia in clinical practice and research.
Assessment of pain and sensory function during regional analgesia contributes to a better understanding of the mechanisms underlying the action of drugs and techniques, and provides information on the effectiveness of regional analgesia in daily practice. Sensory tests only partially mimic clinical pain, mainly because they are artificial and reproduce only a part of the complex experience of p...
متن کاملIntervention research in psychosis: issues related to clinical assessment.
This article discusses efforts to optimize clinical assessment for intervention effectiveness trials. Generalizability is a crucial issue; investigators should choose their inclusion/exclusion criteria to increase subject inclusion and should collect data on the selection process to determine the extent of selection biases. Intervention research requires assessment instruments appropriate for a...
متن کاملThe Assessment of Non-Linear Effects in Clinical Research
Background: Novel models for the assessment of non-linear data are being developed for the benefit of making better predictions from the data. Objective: To review traditional and modern models. Results, and Conclusions: 1) Logit and probit transformations are often successfully used to mimic a linear model. Logistic regression, Cox regression, Poisson regression, and Markow modeling are exampl...
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ژورنال
عنوان ژورنال: Journal of the American College of Cardiology
سال: 1988
ISSN: 0735-1097
DOI: 10.1016/0735-1097(88)90443-3